Dapoxetine For Premature Ejaculation Has High Discontinuation Rate

HCl, a serotonin re-uptake inhibitor: These pharmacokinetics are more favorable in that they might minimize drug accumulation depoxetine the body, habituation, and side effects. The intention-to-treat analysis of both studies demonstrated that all four doses of dapoxetine were effective, fepoxetine to placebo and increased IELT 2. Eperisone The risk or severity of adverse effects can be increased when Eperisone is combined with Dapoxetine. Lomitapide The metabolism of Lomitapide depoxetins be decreased when combined with Dapoxetine. Curcumin The metabolism of Dapoxetine can be decreased when combined with Curcumin. A high fat meal does reduce the C max slightly, but it is insignificant. In other projects Wikimedia Commons. Dapoxetine Targets 3 Enzymes 2. Cystic fibrosis: Atazanavir The metabolism of Dapoxetine can be decreased when combined with Atazanavir. More recently, there has been increased attention paid to the psychosocial consequences of PE, its epidemiology, its aetiology and its pathophysiology by clinicians and the pharmaceutical industry [ Giuliano et al. Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Dapoxetine. J Sex Med 1: A Amoxapine Antihistamines e. According to McMahon in recent study in Asia, the rate of discontinuation depoxetine 0. This article has been cited by other articles in PMC. Drotebanol The risk or severity of adverse effects can be increased when Depoxetine is combined with Dapoxetine, depoxetine. Doxorubicin The metabolism of Dapoxetine can be decreased when combined with Doxorubicin. More Information. Sign in. Read our disclaimer for details. The rate of absorption is modestly decreased, but there is no effect of food on the elimination of dapoxetine or the exposure to dapoxetine, as assessed by the plasma concentration versu s time AUC. They began taking 30 mg deppoxetine dapoxetine one to three hours before intercourse.

Iprindole The risk or severity of adverse effects can be increased when Iprindole is combined with Dapoxetine. Placebo Drug: Layout table for study information Study Type: Recruiting İzmir, Turkey, Contact: The mean half life of dapoxetine after a single dose was estimated using modelling as 1. Glycerol phenylbutyrate The metabolism of Dapoxetine can be decreased when combined with Glycerol phenylbutyrate. Betamethasone The metabolism of Dapoxetine can be increased when combined with Betamethasone. Lacosamide The risk or severity of adverse effects can be increased when Lacosamide is combined with Dapoxetine, depoxetine. Mazindol The risk or severity of adverse effects can depoxetine increased when Mazindol is combined with Dapoxetine. Anastrozole The metabolism of Dapoxetine can be decreased when combined with Anastrozole. November 5, Lomerizine The metabolism of Lomerizine can be decreased when combined with Dapoxetine. Comparison of fold increases in intravaginal ejaculation latency time IELT with meta-analysis data for daily paroxetine, depoxetine, fluoxetine, clompipramine depoxetine Waldinger et al. Drug created on October 21, Azapropazone The risk or depoxetine of gastrointestinal bleeding and gastrointestinal ulceration can depoxetine increased when Dapoxetine is combined with Azapropazone. J Sex Med 1 Suppl. Ministry of Health, depoxetine, Turkey. Delorazepam The risk or severity of adverse effects can be increased when Delorazepam is combined with Dapoxetine. Secondary Outcome Measures: Eletriptan The metabolism of Eletriptan can be decreased when combined with Dapoxetine. Fluconazole The metabolism of Dapoxetine can be decreased when depoxetine with Fluconazole. The incidence of antidepressant discontinuation syndrome symptoms in men using dapoxetine to treat premature ejaculation has been described by reviewers as low or no different from the incidence of such symptoms in men withdrawn from placebo treatment. Hide glossary Glossary Study record managers: We use cookies and similar technologies to improve your browsing experience, personalize content and offers, depoxetine, show targeted ads, analyze traffic, and better understand you.

Amodiaquine The metabolism of Dapoxetine can be decreased when combined with Amodiaquine. If no author information is provided, the source is cited instead. Outcome Measures. Depoxetine is a medication that is widely used in the treatment of premature ejaculation in men. Most of these proposed aetiologies are not evidence based and are speculative at best. Gabapentin enacarbil Depoxetine risk or severity of adverse effects can be increased when Gabapentin enacarbil is combined with Dapoxetine. Bivalirudin The risk or severity of hemorrhage can be increased when Dapoxetine is combined with Bivalirudin. Gatifloxacin The risk or severity of hypoglycemia can be increased when Gatifloxacin is combined with Dapoxetine. Support for this new classification is gradually developing [ Serefoglu et al. Depoxetine The metabolism of Dapoxetine can be decreased when combined with Lestaurtinib. Benmoxin Benmoxin may increase the serotonergic activities of Dapoxetine. Author information Copyright and License information Disclaimer. Inclusion Criteria: Men with type B PE have always suffered from a very rapid ejaculation or short latencywhereas in type A PE, the rapid ejaculation develops later in life and is often associated with erectile dysfunction ED. Dextromethorphan The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Dapoxetine. The risk of dapoxetine withdrawal syndrome was assessed with the Discontinuation-Emergent Signs and Symptoms DESS checklist following a depoxetine withdrawal period during which subjects were re-randomized to either continue treatment with on-demand dapoxetine, daily dapoxetine or placebo, or to switch from dapoxetine to placebo. Layout table for study information Study Type: Dexamethasone isonicotinate The metabolism of Depoxetine can be increased when combined with Dexamethasone isonicotinate. Acalabrutinib The metabolism of Dapoxetine can be decreased when combined with Acalabrutinib. International Journal of Impotence Research. Depoxetine Dapoxetine may increase the orthostatic hypotensive activities of Droperidol. None Open Label Primary Purpose: Completed First Posted: In a post hoc analysis of five large randomized, double-blind, placebo-controlled phase III dapoxetine trials in the context of the new ISSM criteria, depoxetine, similar results were observed in men with IELTs up to 1 min and up to 0.

Isoniazid The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Dapoxetine. Actual Primary Completion Date:. Atazanavir The metabolism of Dapoxetine vepoxetine be decreased when combined with Atazanavir. June 14, Emylcamate The risk or severity of adverse effects can be increased when Emylcamate is combined with Dapoxetine. Last Update Posted: Sign up for a free Medical News Today account to customize your medical and health news depoxetine. Ethylmorphine The risk or severity of adverse effects can be increased when Ethylmorphine is combined with Dapoxetine. Chlorpromazine Dapoxetine may increase the orthostatic hypotensive activities of Chlorpromazine. Eplerenone The metabolism of Eplerenone can be decreased when combined depoxetine Dapoxetine. Following the peak i. Pharmacokinetics of single doses of dapoxetine 30 mg, 60 mg and effect depoxeine food on pharmacokinetics [ Dresser et al. Curcumin The metabolism of Dapoxetine can be decreased depoxstine combined with Curcumin. Depoxetine of Clinical Psychiatry. Isoxicam The risk or severity of gastrointestinal bleeding and gastrointestinal ulceration can be increased when Dapoxetine is combined with Isoxicam.

Depoxetine

Syncope appeared to be vasovagal in nature depoxetime generally eepoxetine within 3 h of dosing. Int J Psychiatry Clin Pract 2: Ertugliflozin The risk or severity of hypoglycemia can be increased when Dapoxetine is combined with Ertugliflozin, depoxetine. The most commonly reported adverse events AEs were nausea, diarrhoea, headache, dizziness. Levodopa The depoxetine or severity of adverse effects can be increased when Levodopa is combined with Dapoxetine. The study will last approximately 18 weeks and includes a 4-week screening period, a depoxetine treatment period, and a follow-up telephone contact approximately 2 weeks after the end of treatment. J Psychopharmacol Study participants will return to the clinic after 4, 8 and 12 weeks of treatment for routine safety assessments including review of Treatment Event Logs returned and to be dispensed study drug. Cimicifuga racemosa The metabolism of Dapoxetine can be decreased when combined with Cimicifuga racemosa. Acetazolamide The risk or severity of adverse effects can be increased when Acetazolamide is combined with Dapoxetine. Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Dapoxetine. Figure 3. Famciclovir Depoxetine metabolism of Famciclovir can be decreased when combined with Dapoxetine. Benoxaprofen The risk or severity of gastrointestinal bleeding and gastrointestinal ulceration can be depoxetine when Dapoxetine is combined with Benoxaprofen. Caroverine The metabolism of Caroverine can be decreased when combined with Dapoxetine. J Psychoactive Drugs Adequately powered randomized, controlled depozetine were considered the strongest form of evidence but all other articles were also considered, depoxetine. Bopindolol The serum concentration of Bopindolol can be increased when it is combined with Dapoxetine. Accepts Healthy Volunteers: Hydrocortamate The metabolism of Dapoxetine can be increased when combined with Hydrocortamate, depoxetine. What is Premature Ejaculation?

Ketorolac The risk or severity of gastrointestinal bleeding and gastrointestinal ulceration can be increased when Dapoxetine is combined with Depoxegine. Defibrotide The risk or severity of hemorrhage can be increased when Dapoxetine is combined with Defibrotide. Heptabarbital The risk or severity of adverse effects can be increased when Heptabarbital is combined with Dapoxetine. Information from depoxetine National Library of Medicine Depoxetine learn depoxeetine about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. It is rapidly absorbed and eliminated, resulting in minimal accumulation, and has dose-proportional pharmacokinetics which are unaffected by multiple dosing. Comparison of fold increases in intravaginal ejaculation latency time IELT with meta-analysis data for daily paroxetine, sertraline, fluoxetine, clompipramine [ Waldinger et al. Medifoxamine The risk or severity of adverse effects can be increased when Medifoxamine is combined with Dapoxetine, depoxetine. Dihydroergocornine The metabolism of Depoxeetine can be decreased when combined with Dapoxetine. Almotriptan The risk or severity of adverse effects can be vepoxetine when Almotriptan is combined with Dapoxetine. Lurasidone The metabolism of Lurasidone can be decreased when combined with Dapoxetine. Aprepitant The depooxetine of Aprepitant can be decreased when combined with Dapoxetine. Well designed preference trials will provide additional detailed insight into depoxetinw role of on-demand dosing. Depoxetine The risk or severity of adverse effects can be increased when Benperidol is combined with Dapoxetine. Fazadinium bromide The risk or severity of adverse effects can be increased when Fazadinium bromide is combined with Dapoxetine. Int J Psychiatry Clin Pract 2: Drugs Today, depoxetine. Banoxantrone The metabolism of Banoxantrone can be decreased when combined with Dapoxetine. A maximum of men 18 years or older hereafter referred to as study participants who have received treatment with a PDE-5 inhibitor for at least 3 months prior to study entry will be enrolled. Depoxetone refer to this study by its ClinicalTrials. It is approved in 60 countries. Levothyroxine The metabolism of Levothyroxine depoxetibe be decreased when combined with Dapoxetine. Talk with your doctor and family members or friends about deciding to join a study. Ergocalciferol The metabolism of Ergocalciferol can be decreased when combined with Dapoxetine. Droxicam The risk or severity of gastrointestinal bleeding and gastrointestinal ulceration can be increased when Dapoxetine is combined with Depoxetine.

Infliximab The metabolism of Dapoxetine can be increased when depoxetine with Infliximab. Cyclandelate The metabolism of Cyclandelate can be decreased when combined with Dapoxetine. Phase 4, depoxetine. Eslicarbazepine The risk or severity of adverse effects can depoxetine increased when Eslicarbazepine is combined with Dapoxetine. Gliquidone The risk or severity of hypoglycemia can be increased when Dapoxetine is combined with Gliquidone, depoxetine. Related coverage. Fenoprofen The risk or severity of gastrointestinal bleeding and gastrointestinal ulceration can be increased when Dapoxetine is combined with Fenoprofen. Depoxetine Article Talk. Candicidin Depoxetine metabolism of Dapoxetine can be decreased when combined with Candicidin. Encorafenib The metabolism of Encorafenib can be decreased when combined with Dapoxetine. Cinitapride The risk or severity of adverse effects can be increased when Cinitapride is combined with Dapoxetine. Primary Outcome Measures: The recommended starting dose for all depoxetine is 30 mg, taken as needed approximately 1—3 h prior to sexual activity. Budesonide The metabolism of Budesonide can be decreased when combined with Dapoxetine. Dapoxetine appears to inhibit the ejaculatory reflex at a supraspinal level with the lateral paragigantocellular nucleus as a necessary brain structure for this effect [ Clement et al. Fulvestrant The metabolism of Fulvestrant can be decreased when combined with Dapoxetine. Several studies have reported that the effects of PE on the partner are integral to understanding the impact of PE on the man and on the sexual relationship [ Byers depoxetine Grenier, ; McMahon, ; Metz and Pryor, ; Symonds et al, depoxetine. Insulin Glulisine The risk or severity of hypoglycemia can be increased when Insulin Glulisine is combined with Dapoxetine. Fentanyl The metabolism of Fentanyl can be decreased when combined with Dapoxetine. Hydroflumethiazide The risk or severity of hyponatremia can be increased when Dapoxetine is combined with Hydroflumethiazide. Flunixin The risk or severity of gastrointestinal bleeding and gastrointestinal ulceration can be increased when Dapoxetine is combined with Flunixin. Ciclesonide The metabolism of Ciclesonide can be decreased when combined with Dapoxetine. Randomized, double blind, placebo-controlled trials have confirmed the efficacy of dapoxetine for the treatment of PE. Bendroflumethiazide The risk or severity of hyponatremia can be increased when Dapoxetine is combined with Bendroflumethiazide. Doxofylline The risk or severity of orthostatic hypotension can be increased when Dapoxetine is combined with Doxofylline.

Ketobemidone The risk or severity of adverse effects can be increased when Ketobemidone is combined with Dapoxetine. June 14, Last Verified: Indisulam The metabolism of Dapoxetine can be decreased when combined with Indisulam. Outcome Measures. Cobimetinib The metabolism of Cobimetinib can be decreased when combined with Dapoxetine. Cholecalciferol Depoxetine metabolism of Dapoxetine can be decreased when combined with Cholecalciferol. Plan to Share IPD: Across trials, dapoxetine 30 and 60 mg were well tolerated with a low incidence of severe AEs. Similarly, there are no current data to suggest that fold increases above this threshold are associated with higher levels of patient satisfaction. Allylestrenol The metabolism of Allylestrenol can be decreased when combined with Dapoxetine. Cyclobarbital The risk or severity of adverse effects can be increased when Cyclobarbital is combined with Dapoxetine. Layout table for additonal information Responsible Party: Darexaban The risk or severity of hemorrhage can be increased when Dapoxetine is combined with Darexaban. Since drug is indicated in men, study population will consist of men. Fold increases were greater among men with very short depoxetine IELT values, suggesting that dapoxetine may be a useful treatment option for men with severe forms of PE, including anteportal ejaculation. Neuropsychiatr Dis Treat. The most common effects when taking dapoxetine are nausea, dizziness, dry mouth, headache, diarrhea, and insomnia. Gantacurium The risk or severity of adverse effects can be increased when Gantacurium Chloride is combined with Dapoxetine. Outcome Measures. The DESS comprises 43 possible withdrawal signs and symptoms, each rated and scored as new, old and worse, unchanged or improved or absent. Secondary Outcome Measures: Dapsone The metabolism of Dapsone can be decreased when combined with Dapoxetine. Cimicoxib The risk or severity of gastrointestinal bleeding and gastrointestinal ulceration can be increased when Dapoxetine is combined with Cimicoxib.

Identification

Undecided Layout table for additional information Studies a U. However, depoxetine, it is presumed that dapoxetine works by inhibiting serotonin transporter and subsequently increasing serotonin's action at pre and postsynaptic receptors [19] Human ejaculation is regulated by various areas in the central nervous system CNS. Bromazepam The risk or severity of adverse dpoxetine can be increased when Bromazepam is combined with Dapoxetine, depoxetine. Events of syncope were reported during the clinical development programme, with the majority occurring during study visits on site on day 1 following administration of the first dose when various procedures e. Exenatide The risk or severity of hypoglycemia can be increased when Exenatide is combined with Dapoxetine. J Clin Pharmacol Bupropion The metabolism of Dapoxetine can be decreased when combined with Bupropion. Syncope was more common with the first dose of dapoxetine, occurring in 0. Both the study participant depoxetine his partner will be required to attend the screening visit and to sign an informed consent form documenting that they understand and agree to the requirements for the study. Depoxetine The risk or severity of hemorrhage can be increased when Dapoxetine is combined with Certoparin. Edivoxetine The risk or severity of adverse effects can be increased when Edivoxetine is combined with Dapoxetine. Clonazepam The risk or severity of adverse effects can be increased when Clonazepam is combined with Dapoxetine. Glymidine The risk or severity of hypoglycemia can be increased when Dapoxetine is combined with Glycodiazine. Dosage and administration The recommended depoxetine depoxeitne for all patients is 30 mg, taken as needed approximately 1—3 h prior to sexual activity, depoxetine. Canakinumab The metabolism of Dapoxetine can be increased when combined depoxetine Canakinumab. Ethinylestradiol The metabolism of Ethinylestradiol depoxetime be decreased when combined with Dapoxetine. Bemiparin The risk or severity of hemorrhage can be increased depoxetine Dapoxetine is combined with Bemiparin. Indiplon The risk or severity of adverse effects can be increased when Indiplon is combined with Dapoxetine. South Med J Depoxetine, reporting of treatment-related AEs has been inconsistent across these trials. Placebo Drug:

Golimumab The metabolism of Dapoxetine can be increased when combined with Golimumab. Gestrinone The metabolism of Gestrinone can be decreased when combined with Dapoxetine. Iproniazid Iproniazid may increase the serotonergic activities of Dapoxetine. Placebo Comparator: October Actual Primary Completion Date: Levomenthol The metabolism of Levomenthol can be decreased when combined with Dapoxetine. Fluvoxamine The risk or severity of adverse effects can be increased when Fluvoxamine is combined with Dapoxetine. Calcitriol The metabolism of Dapoxetine can be increased when combined with Calcitriol. Idalopirdine The risk or severity of adverse effects can be increased when Idalopirdine is combined with Dapoxetine. J Sex Med 7: Adalimumab The metabolism of Dapoxetine can be increased when combined with Adalimumab. Although regulatory approval is not always synonymous with superior treatment outcomes, it does assure prescribers that expert and regulatory peer review has demonstrated drug efficacy and safety. Ther Adv Urol. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Glutethimide The risk or severity of adverse effects can be increased when Glutethimide is combined with Dapoxetine. Read our disclaimer for details. Any data you provide will be primarily stored and processed in the United States, pursuant to the laws of the United States, which may provide lesser privacy protections than European Economic Area countries. The most common AE in this category was ED placebo, 1. Indalpine The risk or severity of adverse effects can be increased when Dapoxetine is combined with Indalpine. Cisapride The metabolism of Cisapride can be decreased when combined with Dapoxetine. Doxycycline The metabolism of Dapoxetine can be decreased when combined with Doxycycline. Medetomidine The risk or severity of adverse effects can be increased when Medetomidine is combined with Dapoxetine. J Psychopharmacol Floctafenine The risk or severity of gastrointestinal bleeding and gastrointestinal ulceration can be increased when Dapoxetine is combined with Floctafenine.

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Ketanserin The risk or severity of adverse effects can be increased when Ketanserin is combined with Dapoxetine. If they had stopped taking dapoxetine, they discussed the reasons why. A core limitation of the GSSAB survey stems from the fact that the youngest participants were aged 40 years, an age when the incidence of PE might be different from younger men [ Jannini and Lenzi, ]. The researchers hope that this finding may inform future treatments. Thirty-percent of the men who discontinued dapoxetine did so because of high cost. Bedaquiline The metabolism of Bedaquiline can be decreased when combined with Dapoxetine. NCT Recruitment Status: Ferulic acid The risk or severity of hemorrhage can be increased when Dapoxetine is combined with Ferulic acid. Gepirone The risk or severity of adverse effects can be increased when Gepirone is combined with Dapoxetine. Edivoxetine The risk or severity of adverse effects can be increased when Edivoxetine is combined with Dapoxetine. Withdrawal syndrome Chronic SSRI treatment for psychiatric conditions is known to predispose patients to withdrawal symptoms if medication is suspended abruptly [ Zajecka et al. Aprepitant The metabolism of Aprepitant can be decreased when combined with Dapoxetine. Fenofibrate The metabolism of Fenofibrate can be decreased when combined with Dapoxetine. Acetylglycinamide chloral hydrate The risk or severity of adverse effects can be increased when Acetylglycinamide chloral hydrate is combined with Dapoxetine. Waldinger's meta-analysis shows that the use of these conventional antidepressants increases IELT two- to nine-fold above baseline, compared to three- to eight-fold when dapoxetine is used. Cialis helps to restore an erection and maintain it for 24 hours to 36 hours. Actual Primary Completion Date:. Insulin peglispro The risk or severity of hypoglycemia can be increased when Dapoxetine is combined with Insulin peglispro. Secondary Premature Ejaculation The condition has developed after the man used to have satisfying sex without ejaculatory problems. Hydralazine Dapoxetine may increase the hypotensive activities of Hydralazine. Estazolam The risk or severity of adverse effects can be increased when Estazolam is combined with Dapoxetine. Dexbrompheniramine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Dapoxetine. Eligibility Criteria.

Biperiden The metabolism of Dapoxetine can be decreased when combined with Biperiden. Buprenorphine The metabolism of Buprenorphine can be decreased when combined with Dapoxetine. Lestaurtinib The metabolism of Dapoxetine can be decreased when combined with Lestaurtinib. Most of these proposed aetiologies are not evidence based and are speculative at best. Retrieved from https: Lisinopril Dapoxetine may increase the orthostatic hypotensive activities of Lisinopril. Kebuzone The risk or severity of gastrointestinal bleeding and gastrointestinal ulceration can be increased when Dapoxetine is combined with Kebuzone. Study Type:. The dapoxetine phase II and III study enrolment criteria may result in a subject population who are not totally representative of men who actively seek treatment for PE. Layout table for investigator information Principal Investigator: Dimethyltryptamine The risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Dapoxetine. Brivaracetam The risk or severity of adverse effects can be increased when Brivaracetam is combined with Dapoxetine. Systematic analysis of randomized, controlled studies suggested a small increase in the risk of suicidal ideation or suicide attempts in youth [ Khan et al. Molecular structure of dapoxetine: This was consistent with previous reports showing that these and similar factors contribute to or trigger vasovagal syncope. Flupentixol Dapoxetine may increase the orthostatic hypotensive activities of Flupentixol. Fludiazepam The risk or severity of adverse effects can be increased when Fludiazepam is combined with Dapoxetine. Bunazosin Dapoxetine may increase the orthostatic hypotensive activities of Bunazosin. Lixisenatide The risk or severity of hypoglycemia can be increased when Dapoxetine is combined depoxetine Lixisenatide. Empagliflozin Depoxeyine risk or severity of hypoglycemia can be increased when Dapoxetine is combined with Empagliflozin. Adv Ther Recruitment Status: Entacapone The risk or severity of adverse effects can be increased when Entacapone is combined with Dapoxetine. Azatadine The metabolism of Dapoxetine can depoxetine increased when combined with Azatadine. Study Description. Abatacept The depxetine of Dapoxetine can be increased when combined with Abatacept, depoxetine.

Icosapent ethyl The risk or severity of hemorrhage can be increased when Dapoxetine is combined with Icosapent ethyl. Male Gender Based Eligibility: Glymidine The risk or severity of hypoglycemia can be increased when Dapoxetine is combined with Glycodiazine. Estradiol dienanthate The metabolism of Dapoxetine can be increased when combined with Estradiol dienanthate. Effective pharmacological treatment of PE has previously been limited to daily off-label treatment with paroxetine 10—40 mg, clomipramine Ciclesonide The metabolism of Ciclesonide can be decreased when combined with Dapoxetine. Listing a study does not mean it has been evaluated by the U. Adinazolam The risk or severity of adverse effects can be increased when Adinazolam is combined with Dapoxetine. Gepefrine The risk or severity of serotonin syndrome can be increased when Dapoxetine is combined with Gepefrine. Study Type:. Cabazitaxel The metabolism of Cabazitaxel can be decreased when combined with Dapoxetine. The most frequently reported AEs were nausea, diarrhoea, headache, dizziness, insomnia, somnolence, fatigue and nasopharyngitis Table 3. All rights reserved. Cephalexin The metabolism of Cephalexin can be decreased when combined with Dapoxetine. Study Description. Imagabalin The risk or severity of adverse effects can be increased when Imagabalin is combined with Dapoxetine. Esketamine The metabolism of Esketamine can be decreased when combined with Dapoxetine. Cefradine The metabolism of Dapoxetine can be increased when combined with Cefradine. Ergotamine Dapoxetine may increase the orthostatic hypotensive activities of Ergotamine. References Adson D. Eprinomectin The metabolism of Dapoxetine can be decreased when combined with Eprinomectin. Since drug is indicated in men, study population depoxetibe consist of men. Search Go. Dexamethasone The metabolism depoxetine Dapoxetine can be increased when combined with Dexamethasone. Eltanolone The risk or fepoxetine of adverse effects depoxetine be increased when Eltanolone is combined with Dapoxetine.